Renostead

Renostead is a combination of N-Acetylcysteine and Taurine that acts synergistically to attenuate glomerular damage and microalbuminaria in diabetic kidney disease patients.

N-Acetylcysteine (also known as N-acetyl-L-cysteine or NAC) is a derivative of cysteine with an acetyl group attached to the amino group of cysteine. NAC is essentially a prodrug that is converted to cysteine (in the intestine by the enzyme aminoacylase) and absorbed in the intestine into the blood stream. Cysteine is a key constituent to glutathione and hence administration of acetylcysteine replenishes glutathione stores.

Taurine is a type of conditionally essential amino acid found throughout the body. It is particularly concentrated in the brain, eyes, heart and muscles. It comprises of over 50% of the total free amino acid pool of the heart. Taurine plays role in several biological processes in the kidney and helps in improving renal blood flow and endothelial cell function. Taurine has been shown to play a role in four different forms of kidney disease: glomerulonephritis, diabetic nephropathy, chronic renal failure, and acute kidney injury

Studies have shown that glomerular damage in diabetes can be prevented or at least attenuated by supplementation with Taurine and N-Acetylcysteine. Also Taurine in combination with
N-Acetylcysteine was useful in attenuating urinary albumin to creatinine ratio and sTGF-β1 levels in microalbuminuric type 2 diabetic patients. The benefits of taurine therapy on kidney function and blood pressure are noteworthy and may be useful in preventing the deterioration of microalbuminuria in diabetic kidney disease patients.

Each tablet of Renostead contains N-Acetylcysteine 150mg and Taurine 500mg.

Renostead should be used as an adjunct therapy in treating following conditions:

1. Diabetic Nephropathy
2. Tubulointerstitial damage
3. Mitochondrial dysfunction
4. Inflammatory Glomerular Injury
5. Chronic Renal Failure

The optimal daily dose of Renostead is 1 tablet twice daily after meals.

Storage : Keep in dry place at a temperature not exceeding 30°C. Protect from light .

10 tablets packed in a strip, 10 such strips packed in a carton